Metabolic remodeling, marked by maladaptive shifts in substrate use and energy production, is a hallmark of pathologic cardiac hypertrophy. Yet the mechanisms linking stress signaling to impaired ...
Background Immune checkpoint blockade (ICB) has limited efficacy in microsatellite stable (MSS) colorectal cancer (CRC) due to an immunosuppressive tumour microenvironment. Although loss of ...
Protein microarrays labelled with fluorophores constitute a versatile platform for high-throughput analysis of protein interactions, expression levels and post-translational modifications. In a ...
Planar waveguide (PWG) technology (right) has the advantage over conventional epifluorescence excitation (left) for surface-confined assays in that only surface-bound fluorphores respond to the ...
Objectives In the complex panorama of autoimmune diseases, the characterisation of pivotal contributing autoantibodies that are involved in disease progression remains challenging. This study aimed to ...
After a Consumer Reports investigation revealed that some popular protein powders and shakes contained troubling levels of lead, many readers wrote in with a simple question: What does this mean for ...
aUsher Institute, Ashworth Laboratories, University of Edinburgh, Edinburgh, UK bInstitute of Immunology and infection Research, Ashworth Laboratories, University of Edinburgh, Edinburgh, UK cTackling ...
Heidelberg, 10 th of June 2025 – PEPperPRINT, a global leader in peptide microarray technology, celebrates its 15 th anniversary with the launch of its next-generation peptide microarray platform: ...
One of the most important concepts in molecular biology is known as the “central dogma”, first coined by Francis Crick in 1958. Crick’s dogma accurately describes the flow of information through ...
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