Recombinant adeno-associated virus (AAV) vectors are predominantly nonintegrating, but rare genomic integration events have been associated with oncogenesis in neonatal murine models. Here we report a ...

The head of a federal arts commission is proposing to replace columns that frame the White House main entrance with a more ornate style favored by President Donald Trump, according to The Washington ...

Ion exchange chromatography (IEX) is a versatile and widely used technique for separating biomolecules based on charge. It plays a critical role in protein purification in research and ...

Biogen has discontinued all gene therapy programs using adeno-associated virus (AAV) capsids, instead shifting resources to modalities that have the highest likelihood of achieving better treatment ...

The first column shifter in America was introduced in 1938, with the goal of freeing up space in the center console for a larger front bench seat. During that time, manual transmissions usually had ...

University of Geneva researchers led a collaboration for testing different size-exclusion chromatography columns to compare the capability for characterizing mRNA. Cell and gene therapies typically ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. HEK293T cells were cultured in 15 × 150 mm Nunc EasYDish dishes ...

Accelerating and de-risking late pre-clinical drug development with the zebrafish tumor xenograft (ZTX) platform. Efficacy and safety data from Ph1b, dose optimization trial of two doses of TH1902 ...

Industry-leading RNA editing activity in the CNS of both mice and non-human primates highlights the broad applicability and therapeutic potential of the RNAfix® platform in CNS diseases Preclinical ...

Amid a reckoning for the gene therapy field, Vertex Pharmaceuticals has joined a growing list of companies paring back their research efforts around the adeno-associated virus (AAV) vectors used to ...