Radical prostatectomy is potentially curative in patients with high-risk localized or locally advanced prostate cancer; however, relapse occurs within 5 years in up to 50% of patients. We ...

The 50-gene Prosigna test identifies most patients with ER-positive, HER2-negative early breast cancer who do not benefit from adjuvant chemotherapy.

Scientists developed a DNA or gene test that can differentiate between patients who are likely to benefit from the treatment and those who are not, a clinical trial has shown.

Many people with breast cancer can safely avoid chemotherapy with the use of a gene test, potentially sparing them unnecessary side effects without increasing the risk of the cancer returning, a large ...

Omitting completion axillary lymph node dissection does not increase risk for death for patients with clinically node-negative breast cancer, but it does significantly improve arm distress.Data from ...

The largest randomized trial of its kind to date found noninferior survival and better arm morbidity among patients with breast cancer who did not undergo completion axillary lymph node dissection.

Historically, a positive SLNB necessitated completion ALND to ensure removal of additional cancer that lymph nodes might harbor, said de Boniface. Axillary surgery may lead to multiple arm-related ...

Five-year OS was 94.4% with ALND omission vs 93.4% with completion ALND (HR 0.89), confirming non-inferiority; breast cancer–specific survival was similarly high in both arms. Inclusion of mastectomy ...

Thousands of women could now be spared one of the most debilitating side-effects of breast cancer treatment - lifelong ...

An international study led by University College London (UCL) has found that many people over 40 with hormone-sensitive ...

Warning: This article contains discussion of cancer which some readers may find distressing. In February 2025, Holly Stubbs was 31 weeks pregnant with her third child when she noticed a lump on her ...

Christy Redican grew up in Connecticut, spending summers sailing and playing tennis. “I was a sun worshipper,” she said. “I did all the things you’re not supposed to do. I have fair skin, blonde hair ...