CFTR is a plasma membrane, cAMP-activated Cl − channel that is expressed in functionally diverse tissues, including kidney, pancreas, intestine, heart, vas deferens, sweat duct and lung. In epithelial ...
Cystic fibrosis is a genetic disorder driven by CFTR mutations that affects the exocrine glands. Manifesting with excessively viscous mucus production, patients typically experience obstruction of ...
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