ahajournals.org

Early Transcriptional Changes in Neutrophil‐Mediated Processes Following Recanalization After Ischemic Stroke

Ischemic stroke is a leading cause of death and long‐term disability worldwide. Recanalization therapies, including thrombolysis and mechanical thrombectomy, restore blood flow, yet many patients ...
Frontiers

Integrative single-cell RNA-seq and ATAC-seq analysis reveals the key role of inflammatory cell activation in pulmonary arterial hypertension

In this study, scRNA-seq and scATAC-seq were performed to establish a transcriptional and chromatin accessibility atlas in a PAH model, and the key molecules and regulatory mechanisms involved in ...
Frontiers

HYAL3 as a therapeutic target for pulmonary arterial Hypertension–Cardiomyopathy comorbidity: an integrative analysis combined with machine learning and SHAP value interpretation

This study aimed to elucidate the molecular mechanisms driving the comorbidity of pulmonary arterial hypertension and cardiomyopathy (PAH-CMP), identify key pathogenic genes, and explore potential ...
GitHub

GO_KEGG enrichment analysis.R

go <- enrichGO(gene = gene, OrgDb = org.Hs.eg.db, pvalueCutoff = 0.05, qvalueCutoff = 0.05, ont = "all", readable = T) write.table(go, file = "GO_results.txt", sep ...