Professional antigen-presenting cells—monocytes and macrophages—engulf these proteins, digest them into short peptide ...

First investigational PD-(L)1xVEGF bispecific immunomodulator to present global data showing encouraging efficacy in combination with ...

T cell checkpoint modulation harnesses or inhibits natural regulatory pathways that control T cell activation, proliferation and survival. Central to this approach are inhibitory receptors such as ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial ...

T cells lie at the heart of adaptive immunity, recognising peptide antigens via the T cell receptor (TCR) and undergoing activation only when signals from co-stimulatory receptors complement antigen ...

One-time infusion of IMA203CD8 PRAME cell therapy in the ongoing Phase 1 dose escalation/dose expansion trial achieved anti-tumor activity in ...

Onc.AI, a digital health company developing computational biomarkers and decision-support products in oncology using Deep Learning imaging AI, today announced positive external validation results for ...

The Lafayette Parish Sheriff's Office has taken issue with a report of an arrest by ICE agents in an online news source.

Durvalumab monotherapy did not meet the prespecified statistical threshold for DFS versus active monitoring, despite a 6-point absolute 3-year DFS difference (78% vs 72%). RAMPART enrolled ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial "checkpoint" that enables dendritic cells to efficiently activate T ...

Tumor immune surveillance plays a pivotal role in preventing tumor formation, progression, and metastatic spread. However, cancer cells exploit several ...

The interplay between immune responses and cell death pathways is a central theme in immunology and pathology. Recent developments emphasize that these ...