Nitrogen is an essential part of many of the cell’s building blocks, including amino acids and nucleotides, which form proteins and DNA respectively. Therefore, nitrogen has to be available to cells ...
Carbon dioxide (CO 2) electrocatalytic reduction driven by renewable electricity can solve the problem of excessive CO 2 emissions. Since CO 2 is thermodynamically stable, efficient catalysts are ...
Reductive amination of carbonyl compounds with primary amines is a well-established synthetic methodology for the selective production of unsymmetrically substituted secondary and tertiary amines.
Chiral α-tertiary amines can be accessed directly through the electrophilic amination of α-branched ketones utilizing di-tert-butyl azodicarboxylate as the electrophilic nitrogen source. This process, ...
An organocatalytic asymmetric decarboxylative amination reaction of β-keto acids is described. Under mild reaction conditions, a series of chiral α-amino ketones were obtained in good to high yields ...
Flashes of light help chemists at Princeton University and Bristol-Myers Squibb drive the hydroaminations of olefins to produce substituted amines. The light-powered reaction gives chemists another ...