Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body? There are instances where killer T cells—which are meant to precisely remove virus-infected ...

Active aldehydes drive T cell exhaustion in the tumor microenvironment This motivated a team of researchers from Kyoto University to investigate this conundrum. A key physiological role of FAO is the ...

Why structure matters: Scientists modeled how the thymus develops its convoluted shape, showing it boosts the elimination of ...

Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a ...

Scientists have identified a reason why certain crucial immune cells lose their vigour inside a tumour: their mitochondria become debilitated, according to a study 1 in mice. These immune cells, ...

The best time to get an infection might be after a meal, suggest experiments in mice and humans that found that certain immune cells, known as T cells, seem to get a boost from food. The findings, ...

The colorful dots at the center are cytotoxic granules used to destroy infected or cancerous cells. Credit: F. Lemaitre @ ...