Post-translational modifications (PTMs) of tubulin, including acetylation, glutamylation and detyrosination, play a critical role in dictating the dynamic behaviour and specialised functions of ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

One of the first things that students learn when they enter a biology class is the central dogma: DNA → messenger RNA → proteins. Only about 3% of the human genome directly codes for proteins, which ...

The top panel, designed with BioRender.com, illustrates the process of clot formation and lysis, beginning with platelet aggregation and activation of the coagulation cascade, followed by the ...

This multidisciplinary project integrates computational biology, structural modelling, population genomics, and AI. It will provide new mechanistic insights into how coding variation and PTMs ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Promise Bio, a company pioneering precision medicine solutions using epiproteomics and artificial intelligence, today announced the launch of the Frontier Epiproteomic Innovation Grant, an R&D access ...

Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies"). New research led by Boston Children's Hospital challenges the current ...

An Iowa State University research team has discovered a method for modifying the function of an enzyme crucial to fat production, which could lead to more effective treatments for childhood obesity ...