The latest gene therapy treatments that are working through clinical trials are targeting problems that are localized in the body. Eventually there will be gene therapy success on non-localized ...
To investigate the effect of the NLS on integration in an in vivo gene therapy setting, we performed hydrodynamic tail-vein injection on groups of 5–7 mice with the NLS-containing integrase constructs ...
Nuclear Factor-kappaB (NF-κB) plays a central role in regulating the key mediators of inflammation involved in acute lung injury. The anti-inflammatory effect of steroids by suppressing ...
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