Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Researchers have published guidelines for the design of new molecules with pharmacological potential for the treatment of a wide range of diseases, including prostate cancer. These peptidic molecules, ...

Researchers use machine learning to assign ‘fingerprints’ to proteins based on their surface affinity alone, predicting which proteins would interact based on these molecular fingerprints. A study led ...

Learn how experts in various techniques, such as surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC), measure protein–protein interactions (PPIs) for therapeutic development.

Scientists have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication. The computational tool is ...

The pros and cons of moonlighting—taking up an extra job in addition to full-time employment—are hotly debated. But in biology, moonlighting is not uncommon, as individual proteins often perform ...

Cells constantly monitor and recycle their proteins through a tightly regulated waste-disposal system. Proteins that are no ...

Results of thioflavin T fluorescence analyses revealed a drastic increase in the fluorescence intensity when BSA was mixed with ultra-small (10 nm) silica nanoparticles (NPs) with a stirring time of ...

Expression proteomics determines where and when proteins are expressed and measures their quantities. This qualitative and quantitative approach can compare protein expression across conditions, such ...