These models can be used either offline to provide the optimal process cycle, or online to provide optimal, real-time process control [3]. This is the target of the iREMO project (www.iremo.eu), an EC ...

In a recent article, a U.K. group outlined their vision for downstream process analytic technology (PAT) and quality by design (QbD) within the context of batch vs. continuous chromatography. The ...

Reaching Bioprocessing 4.0 depends on advanced methods of monitoring and control. For an update on these methods, GEN has organized this roundtable discussion. It presents the insights of four experts ...

Precision grinding of bearing rings and rollers is a well established process, one that has been applied, tested, and analyzed over many years. Until recently, the common view among many grinding ...

"The problem with paperwork is, if you had a 12-hour shift, you finish your paper work 11-and-a-half hours after that person started the machine," Gattshall explains. "That's the point where you look ...

Technology progression within advanced process control (APC) continues to evolve; however, it is the relationship among core APC developments, enabling technologies, and management practices that is ...