Angiogenesis is a complex cascade of events involving extensive interplay between cells, soluble factors and extra-cellular matrix components. Soluble factors including cytokines have a stimulatory or ...

Heart failure is a complex clinical syndrome. There is evidence for a genetic contribution to the pathophysiology of heart failure. Considering the fundamental role of neurohormonal factors in the ...

Phase I Trial of Yttrium-90—Labeled Anti—Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Androgen-Independent Prostate Cancer In the future, we will invariably see much more on ...

Polymorphisms in cytokine genes can influence immune responses, inflammation, and tissue injury and may affect the outcome of hematopoietic stem-cell transplantation. Among recipients of hematopoietic ...

What are Single Nucleotide Polymorphisms? Single nucleotide polymorphisms (SNPs) are variations in a genome’s base pair in a DNA sequence, and occur in approximately 1 out of 800 base pairs. These ...

“We found that VNTRs can influence gene expression through changes in length or motif dosage,” said Prof. HE. The researchers also examined the distribution patterns of VNTR polymorphisms across ...

Clinical observations of inherited differences in drug effects were first documented in the 1950s, 6–9 giving rise to the field of pharmacogenetics, and later pharmacogenomics. Although the two terms ...

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis ...