Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But a critical aspect underlying the machinery of protein manufacture has long ...

The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify ...

An essential component of living cells, the nucleolus underwent a major evolutionary shift around 300m years ago. Scientists have solved an age-old mystery in biology by discovering a protein found in ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

The size of a cell's nucleolus may reveal how long that cell, or even the organism it belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link between ...

Eukaryotic cells have specialized structures that complete specific tasks - organelles. One of those organelles is the nucleolus, which is known to generate subunits of another organelle, the ribosome ...

Ribosomes carry out the cell's most essential function-translating genetic information into proteins. But even though scientists understand much about how these protein generators are formed, their ...