In the world of biomedical research, the humble lab mouse is a superstar—it’s easy enough to rear in large quantities, shares a considerable amount of core biological processes with humans, and is ...

Antibody therapies work in part by binding to Fc receptors, proteins found on immune cells that control key immune functions such as antibody-mediated cell killing and inflammation. Since these ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Genetically altered mice are valuable tools in biomedical research. The Mutant Mouse Resource and Research Center, located at UC Davis and supported by a grant from NIH, has been providing a national ...

Antibody therapies are changing the treatment of cancer, inflammatory diseases and infections. However, many promising drug ...