Chronic inflammation is acknowledged as the fundamental cause of various pathological conditions, and in recent decades, there has been a growing focus on ...

A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell clearance and limiting inflammatory gene activity.

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. It’s just as important to be able to resolve that inflammation and ...

A study published in Immunity reveals that type I interferons (IFN‑I) help resolve inflammation by inducing changes in macrophage mitochondria When our body fights an infection, the immune system must ...

The medical community increasingly recognizes chronic inflammation as a fundamental driver behind numerous health conditions, from obvious manifestations like rheumatoid arthritis and inflammatory ...

Inflammation sits at the heart of everything from sprained ankles to heart disease, yet medicine has long struggled to switch it off without blunting the immune system entirely. Now scientists have ...

In IAV-infected wild-type AECII, ELOVL5 promoted inflammation resolution and cell proliferation through both regulating lipid metabolism (promoting PUFAs generation while decreasing eicosanoid levels) ...

Find out more about how intermittent fasting reduced Crohn’s disease symptoms and inflammation in a randomised clinical trial.

Skin manifestations are common in patients with SLE. A recent study reported increased site-specific recurrence of cutaneous lupus erythematosus (CLE).1 While this study included a proportion of ...