The drug is specifically approved to treat blastic plasmacytoid dendritic cell neoplasm (an ultra-rare and aggressive type of ...

AbbVie ABBV announced the FDA approval of Decnupaz (pivekimab sunirine-pvzy) for the treatment of adult patients with blastic ...

The CD123-directed antibody and alkylating agent conjugate led to complete remission or clinical complete remission in nearly ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

A team of scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Hospital de la Princesa-UAM in Madrid have discovered that dendritic cells, an important cell type in the ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial "checkpoint" that enables dendritic cells to efficiently activate T ...

A new study suggest that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for ...

Complete remission rate of 69% in blastic plasmacytoid dendritic cell neoplasm ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...