In a recent study published in Nature Communications, researchers performed genome-wide copy number profiling of the androgen receptor (AR) on metastases from deceased prostate cancer patients. Study: ...

Various approaches have been developed to identify and quantitate copy-number variation. A new, high-resolution approach that already shows promise is digital PCR. As illustrated by many research ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

Association of Timely Comprehensive Genomic Profiling With Precision Oncology Treatment Use and Patient Outcomes in Advanced Non–Small-Cell Lung Cancer Somatic chromosomal alterations, particularly ...

CN signatures were prevalent across cancer types and associated with diverse processes including focal tandem duplications, seismic amplifications, genome-wide loss of heterozygosity (gLOH), and HRD.

Understanding the relationship between mtDNA and animal growth could provide valuable information for selective breeding in aquaculture. However, the complex interactions between genetics and ...