As rare disease trials face persistent feasibility challenges, Bayesian designs are gaining momentum by enabling more ...

In 2022, Rafael Nadal approached the baseline and began horizontally abducting his right arm to loft a tennis ball approximately 5 feet. He abruptly contacted the inferolateral aspect of the tennis ...

In today's ACT Brief, we explore how Bayesian approaches are powering studies in rare disease and pediatrics, a major public-private initiative is standardizing digital endpoints for regulatory ...

In a new draft guidance issued on January 14, 2026, the FDA discussed the use of a modern statistical methodology in clinical trials designed to show the effectiveness of a new drug. The guidance, ...

Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit NAP.edu/10766 to get more information about this ...

Pennington Biomedical Research Center hosted the NIDDK Clinical Methods for Nutrition and Obesity Research Course, an intensive four-day training program designed to equip postdoctoral fellows, ...

Researchers introduce a novel, detailed immune-profiling method that measures modifications to DNA without requiring fresh samples or intact cells. The technology uses minimal sample input, works with ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

Method of treatment patents based on Phase II and Phase III clinical trial protocols are routinely pursued to extend patent exclusivity and strategically build a patent portfolio for a drug asset. The ...