The cell cycle is governed by a network of surveillance mechanisms that detect DNA lesions and coordinate repair with progression through G1, S, G2 and M phases. Central to this system are sensor ...
A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...
Red indicates mouse embryonic stem cells and green indicates mouse epiblast stem cells. The two cell types were co-cultured under GSK3α inhibition and maintained their distinct identities. A study ...