A new Nature Communications study reveals how the common AML mutation NPM1c+ exploits failures in mitotic chromosome ...

A research team led by professor Chan Kui-ming from the Department of Biomedical Sciences at CityUHK discovered that H2BE113K ...

Researchers in Adelaide and Singapore have uncovered new clues as to why some people with chronic myeloid leukemia (CML) ...

Scientists have traced a devastating pattern of brain cell loss in a handful of families to a single, ultra-rare mutation that sabotages one of the brain’s key protective enzymes. The discovery not ...

Add Yahoo as a preferred source to see more of our stories on Google. Experiments on an ultra-rare genetic mutation that causes neurodegeneration in children have helped uncover a new mechanism by ...

An exploration of large patient biobanks linked to clinical information has revealed new health conditions associated with sickle cell trait, the status of carrying just one beta globin gene with the ...

Biomedical engineers at Duke University have developed a three-layer model of human blood vessels that enables researchers to ...

In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...

In mouse bone marrow, mesenchymal stem cells (red), which normally nurture blood stem cells, produce a signal that is attractive for monocytes (green). The monocytes in turn prod nearby blood stem ...

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the ...