Combination of growth factor gene-enhanced cartilage matrix synthesis with interleukin-1 receptor antagonist protein (IL-1Ra) abrogation of cartilage matrix degradation may reduce and possibly reverse ...

Announcing a new publication for Acta Materia Medica journal. Traditional Chinese medicine has shown therapeutic potential in treating osteoarthritis (OA) by regulating inflammation and maintaining ...

A working group develops strategies for regeneration of articular cartilage and has found that natural cartilage matrix is suitable as a biomaterial for improved cartilage regeneration. Just a few ...

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving "dancing molecules," to repair tissues and reverse paralysis after severe spinal ...

Current intra-articular drug delivery methods do not guarantee sufficient drug penetration into cartilage tissue to reach cell and matrix targets at the concentrations necessary to elicit the desired ...

In patients with severe osteoarthritis, cartilage can wear so thin that joints essentially transform into bone on bone — without a cushion between. A new therapy that uses synthetic nanofibers to ...

The Orthopaedic Research and Education Foundation 2026 Career Development Grant, was awarded to Alvin Su, MD, PhD, and his team for biologics research. according to a May 21 news release. The $300,00 ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

Regenerative medicine holds promise for the treatment of degenerative and genetic diseases. One goal is to rejuvenate damaged tissue by establishing processes for the transplantation of pluripotent or ...

Researchers have identified the SHP protein as a key regulator that suppresses cartilage-degrading enzymes and slows osteoarthritis progression.