A research team led by professor Chan Kui-ming from the Department of Biomedical Sciences at CityUHK discovered that H2BE113K ...

Inheriting a mutation in BRCA1 or BRCA2 puts you at higher risk of breast, prostate, ovarian and pancreatic cancer. Genetic testing and screening can be life-saving.

A multicancer genomic analysis links mitochondrial DNA copy number with mutation burden and gene expression relevant to ...

A new computational pipeline called HiFIseek systematically links damaging non-coding mutations to cancer genes, revealing ...

Mathematical modelling shows that elevated mutation rates and mutational biases, rather than altered selection, can explain ...

Germline genetic screening can identify whether a patient with cancer has inherited genetic alterations in a gene or genes ...

A single sperm donor who carries a rare cancer-causing genetic mutation has fathered at least 197 children across 14 countries in Europe, according to a collaborative investigation by 14 European news ...

Non‑smokers with high‑risk traits show up to 32.3% prevalence of germline pathogenic variants in DNA repair genes ...

For decades, society has viewed lung cancer through a singular, judgmental lens: It is the “smoker’s disease.” But a ...

KRAS mutations lead to excessive cell growth due to alterations in the KRAS gene. They are present in a significant percentage of non-small cell lung cancers (NSCLC). Diagnosis involves testing ...

The gene is found predominantly in Southern Appalachia and may be one of the most powerful cancer-risk mutations ever found.

While widespread awareness of breast cancer has helped save lives, persistent myths about the disease continue to cause ...