Targeted extended circulation LNP incorporating DARPins achieved complete B cell depletion in nonhuman primates through highly specific in vivo CD8+ T cell engineeringRobust study quantifies ...
Enantioselective α-alkylation of carbonyl is considered as one of the most important processes for asymmetric synthesis. Common alkylation agents, that is, alkyl halides, are notorious substrates for ...
Oxidizing the end carbon atom of a terminal alkene to form an aldehyde, a process called anti-Markovnikov alkene oxidation, is difficult because the reaction is energetically unfavorable. The ...
Histones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. A team of researchers at Nagoya University in ...
Aldehyde dehydrogenase 2 (ALDH2) is an important enzyme that detoxifies harmful aldehydes produced in the body. While it is best known for metabolizing acetaldehyde—an aldehyde increased by ...
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